BIOMATNANO4AD project receives an “Excellent” rating from the FCT.

The research project BIOMATNANO4AD – Bioinspired materials in nanosolutions to tackle atopic dermatitis received an excellent evaluation from the Portuguese Foundation for Science and Technology (FCT), standing out for its strong scientific performance and the successful achievement of its main objectives.

Led by CBIOS, the project was developed in partnership with EntoGreen, a Portuguese biotechnology company, LAQV-REQUIMTE, and the University of Vienna.

According to the evaluation panel, the team developed and optimised several lipid nanoparticles incorporating insect oil, ceramides and ionic liquids for the delivery of glucocorticoids. These systems were thoroughly characterised and demonstrated promising physicochemical properties, long-term stability, and biocompatibility, both in vitro and in vivo. One of the formulations showed potential to advance to pre-clinical testing, fulfilling the project’s main objective.

The panel highlighted the successful completion of all core tasks, including the partial assessment of safety and efficacy. In terms of outcomes, the project demonstrated high scientific productivity. Five peer-reviewed international papers were successfully published, which is considered a highly significant achievement given the scope and duration of the exploratory project.

Dissemination activities also exceeded expectations, including extensive participation in national and international conferences through oral and poster presentations, as well as the organisation of scientific events and public engagement initiatives. The project also made a significant contribution to advanced training, with several completed and ongoing master’s dissertations, alongside a PhD thesis currently under development.

Overall, the final evaluation recognises BIOMATNANO4AD as a highly productive and impactful project, combining scientific excellence with strong societal engagement and meaningful contributions to the fields of biomaterials and nanotechnology applied to skin health.

More information about the project’s outputs and activities is available at: https://biomatnano4ad.wixsite.com/biomatnano4ad